Animal disease research
نویسندگان
چکیده
منابع مشابه
Animal models for Gaucher disease research
Gaucher disease (GD), the most common lysosomal storage disorder (LSD), is caused by the defective activity of the lysosomal hydrolase glucocerebrosidase, which is encoded by the GBA gene. Generation of animal models that faithfully recapitulate the three clinical subtypes of GD has proved to be more of a challenge than first anticipated. The first mouse to be produced died within hours after b...
متن کاملResearch of Animal Disease Information System Based on GIS Technology
It is necessary to build animal disease information system in order to dynamically monitor and predict diseases distribution, and propagation, such as HPAI and FMD taking place, Powerful functions of data management analysis and display with the GIS can be applied oriented to animal disease information. This disease information platform can be applied to dynamiclly monitor and predict disease, ...
متن کاملCurrent Animal Models of Alzheimer’s Disease: Challenges in Translational Research
In their article, Franco and CedazoMinguez open the debate on why it is difficult to translate successful preclinical research in Alzheimer’s disease (AD) mouse models into clinical practice (1). Here, we discuss some aspects that should be taken into account regarding the main discrepancies that exist between the current animal models and the disease in humans. The translation of findings from...
متن کاملResearch progress on hepatic encephalopathy: animal models and disease mechanisms
Hepatic encephalopathy (HE) is a hepatic disease with neuronal confusion, altered level of consciousness, and coma as a result of severe liver damage/failure. HE is with complicated pathological mechanisms and high mortality, which seriously affects patients' daily life. Roughly, it can be divided into three types, A, B and C. Type A is acute HE and Types B and C are chronic. At present, the pa...
متن کاملNatural Non-Trasgenic Animal Models for Research in Alzheimer’s Disease
The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human Abeta precursor protein (APP) and/or some of the enzymes implicated in their metabolic processing. However, these transgenic mice carry their own APP and APP-processing enzymes, which may interfere in the production of different amyloid-beta (Abeta) peptides e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Veterinary Journal
سال: 1988
ISSN: 0007-1935
DOI: 10.1016/0007-1935(88)90041-3